Title : Levodopa induces synthesis of nerve growth factor and growth hormone in patients with Parkinson disease.

Pub. Date : 2011 May-Jun

PMID : 21543973






5 Functional Relationships(s)
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1 Levodopa induces synthesis of nerve growth factor and growth hormone in patients with Parkinson disease. Levodopa growth hormone 1 Homo sapiens
2 Levodopa may experimentally exert supportive effects on nerve growth factor synthesis and on growth hormone production, a hormonal compound with regenerative potential. Levodopa growth hormone 1 Homo sapiens
3 OBJECTIVE: The objective of this study was to investigate the effects of soluble 250-mg levodopa/benserazide administration on plasma occurrence of levodopa, nerve growth factor, and growth hormone in patients with Parkinson disease over an interval of 60 minutes. Levodopa growth hormone 1 Homo sapiens
4 RESULTS: Levodopa moderately increased bioavailability of nerve growth factor and growth hormone combined with the rise of levodopa. Levodopa growth hormone 1 Homo sapiens
5 CONCLUSIONS: Axonal degeneration may not be due to levodopa itself, as levodopa supports production of nerve growth factor and of growth hormone. Levodopa growth hormone 1 Homo sapiens