Title : Molecular recognition at the active site of catechol-O-methyltransferase (COMT): adenine replacements in bisubstrate inhibitors.

Pub. Date : 2011 May 27

PMID : 21538606






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 COMT catalyzes the transfer of an activated methyl group from S-adenosylmethionine (SAM) to its catechol substrates, such as L-dopa, in the presence of magnesium ions. S-Adenosylmethionine catechol-O-methyltransferase Homo sapiens
2 COMT catalyzes the transfer of an activated methyl group from S-adenosylmethionine (SAM) to its catechol substrates, such as L-dopa, in the presence of magnesium ions. S-Adenosylmethionine catechol-O-methyltransferase Homo sapiens
3 The molecular recognition properties of the SAM-binding site of COMT have been investigated only sparsely. S-Adenosylmethionine catechol-O-methyltransferase Homo sapiens