Title : The transient catalytically competent coenzyme allocation into the active site of Anabaena ferredoxin NADP+ -reductase.

Pub. Date : 2012 Jan

PMID : 21538059






2 Functional Relationships(s)
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1 In particular, the side chain of the C-terminal Y303 in Anabaena FNR appears key to providing the optimum geometry by reducing the stacking probability between the isoalloxazine and nicotinamide rings, thus providing the required co-linearity and distance among the N5 of the flavin cofactor, the C4 of the coenzyme nicotinamide and the hydride that has to be transferred between them. Niacinamide ferredoxin reductase Homo sapiens
2 In particular, the side chain of the C-terminal Y303 in Anabaena FNR appears key to providing the optimum geometry by reducing the stacking probability between the isoalloxazine and nicotinamide rings, thus providing the required co-linearity and distance among the N5 of the flavin cofactor, the C4 of the coenzyme nicotinamide and the hydride that has to be transferred between them. Niacinamide ferredoxin reductase Homo sapiens