Title : The TIR/BB-loop mimetic AS-1 prevents cardiac hypertrophy by inhibiting IL-1R-mediated MyD88-dependent signaling.

Pub. Date : 2011 Sep

PMID : 21533832






1 Functional Relationships(s)
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1 Recent studies have shown that the TIR/BB-Loop mimetic (AS-1) disrupted the interaction of MyD88 with the IL-1R, resulting in blunting of NF-kappaB activation. boeravinone B interleukin 1 receptor type 1 Homo sapiens