Title : Lysyl oxidase contributes to mechanotransduction-mediated regulation of transforming growth factor-β signaling in breast cancer cells.

Pub. Date : 2011 May

PMID : 21532881






1 Functional Relationships(s)
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1 The ability of TGF-beta1 to activate Smad2/3 was unaffected by LOX inactivation in normal MECs, whereas the stimulation of p38 MAPK by TGF-beta1 was blunted by inhibiting LOX activity in malignant MECs or by inducing the degradation of hydrogen peroxide in both cell types. Hydrogen Peroxide mitogen-activated protein kinase 14 Mus musculus