Title : L-carnitine ameliorates cancer cachexia in mice by regulating the expression and activity of carnitine palmityl transferase.

Pub. Date : 2011 Jul 15

PMID : 21532335






3 Functional Relationships(s)
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1 In the present study, we aim to assess the effects of L-carnitine on the activity and expression of CPT I and II in the liver of cachectic cancer mice. Carnitine carnitine palmitoyltransferase 1b, muscle Mus musculus
2 These effects of L-carnitine on cancer cachexia mice were accompanied by the upregulation of mRNA level of CPT I and II and increased enzyme activity of CPT I in the liver, as well as the downregulation of serum TNF-alpha and IL-6 levels. Carnitine carnitine palmitoyltransferase 1b, muscle Mus musculus
3 These effects of L-carnitine on cancer cachexia mice were accompanied by the upregulation of mRNA level of CPT I and II and increased enzyme activity of CPT I in the liver, as well as the downregulation of serum TNF-alpha and IL-6 levels. Carnitine carnitine palmitoyltransferase 1b, muscle Mus musculus