Title : Assessment of UDP-glucuronosyltransferase catalyzed formation of Picroside II glucuronide in microsomes of different species and recombinant UGTs.

Pub. Date : 2011 Jul

PMID : 21524190






1 Functional Relationships(s)
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1 In addition, both mycophenolic acid (substrate of UGT1A9) and emodin (substrate of UGT1A8 and UGT1A10) could inhibit the glucuronidation of Picroside II with the half maximal inhibitory concentration (IC(50)) values of 173.6 and 76.2 muM, respectively. Mycophenolic Acid latexin Homo sapiens