Title : Sprouty is a cytoplasmic target of adenoviral E1A oncoproteins to regulate the receptor tyrosine kinase signalling pathway.

Pub. Date : 2011 Apr 26

PMID : 21518456






1 Functional Relationships(s)
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1 SRE and TRE reporter assays demonstrated that co-expression of Spry1 with E1A(13S) abolishes the inhibitory function of Spry1 in RTK signalling, which is consequently accompanied with a decrease of E1A13S-induced gene expression. 5-chloro-3-tert-butyl-2'-chloro-4'-nitrosalicylanilide ret proto-oncogene Homo sapiens