Pub. Date : 1990 Nov 27
PMID : 2150818
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The mixed 5-HT1C/2 receptor antagonists, ritanserin and ICI 169,369, did not modify the action of 8-OH-DPAT alone but abolished the potentiation of 8-OH-DPAT-induced tail-flicks by DOI and TFMPP. | 8-Hydroxy-2-(di-n-propylamino)tetralin | 5-hydroxytryptamine receptor 2C | Rattus norvegicus |
| 2 | A common property of those drugs potentiating 8-OH-DPAT-induced tail-flicks is an agonist action at 5-HT1C receptors and the data indicate that it is this mechanism which underlies the facilitation of tail-flicks. | 8-Hydroxy-2-(di-n-propylamino)tetralin | 5-hydroxytryptamine receptor 2C | Rattus norvegicus |