Title : Azithromycin acts as an immunomodulatory agent to suppress the expression of TREM-1 in Bacillus pyocyaneus-induced sepsis.

Pub. Date : 2011 Aug 30

PMID : 21507332






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Azithromycin acts as an immunomodulatory agent to suppress the expression of TREM-1 in Bacillus pyocyaneus-induced sepsis. Azithromycin triggering receptor expressed on myeloid cells 1 Homo sapiens
2 The purpose of the current study was to determine whether azithromycin, a type of macrolide antibiotic, could reduce the expression of TREM-1 in Bacillus pyocyaneus-induced sepsis in vitro and in vivo. Azithromycin triggering receptor expressed on myeloid cells 1 Homo sapiens
3 However, treatment with TREM-1/Fc fusion protein or azithromycin reduced the effect of LPS-stimulated TREM-1 protein expression. Azithromycin triggering receptor expressed on myeloid cells 1 Homo sapiens