Title : Development of 68Ga-labeled mannosylated human serum albumin (MSA) as a lymph node imaging agent for positron emission tomography.

Pub. Date : 2011 Apr

PMID : 21492786






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1 Here, we describe the development of a novel positron-emitting SLN imaging agent labeled with (68)Ga. METHODS: A mannosylated human serum albumin (MSA) was synthesized by conjugating alpha-d-mannopyranosylphenyl isothiocyanate to human serum albumin in sodium carbonate buffer (pH 9.5), and then 2-(p-isothiocyanatobenzyl)-1,4,7-triazacyclononane-1,4,7-triacetic acid was conjugated to synthesize NOTA-MSA. sodium carbonate albumin Mus musculus