Title : Evaluation of 6β-hydroxycortisol, 6β-hydroxycortisone, and a combination of the two as endogenous probes for inhibition of CYP3A4 in vivo.

Pub. Date : 2011 Jun

PMID : 21490593






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The maximum in vivo inhibition was 59%, suggesting that f(m,CYP3A4) for cortisol and cortisone 6beta-hydroxylation is ~60%. Hydrocortisone cytochrome P450 family 3 subfamily A member 4 Homo sapiens