Pub. Date : 2011 Jun 10
PMID : 21489990
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In the normal brain, tau protein is phosphorylated at a number of proline- and non-proline directed sites, which reduce tau microtubule binding and thus regulate microtubule dynamics. | Proline | microtubule associated protein tau | Homo sapiens |
| 2 | In the normal brain, tau protein is phosphorylated at a number of proline- and non-proline directed sites, which reduce tau microtubule binding and thus regulate microtubule dynamics. | Proline | microtubule associated protein tau | Homo sapiens |
| 3 | In the normal brain, tau protein is phosphorylated at a number of proline- and non-proline directed sites, which reduce tau microtubule binding and thus regulate microtubule dynamics. | Proline | microtubule associated protein tau | Homo sapiens |
| 4 | In the normal brain, tau protein is phosphorylated at a number of proline- and non-proline directed sites, which reduce tau microtubule binding and thus regulate microtubule dynamics. | Proline | microtubule associated protein tau | Homo sapiens |
| 5 | Furthermore, in Egr-1(-/-) mouse brain, Cdk5 activity was decreased, PP1 activity was increased, and tau phosphorylation was reduced at both proline-directed and non-proline-directed sites. | Proline | microtubule associated protein tau | Homo sapiens |
| 6 | Furthermore, in Egr-1(-/-) mouse brain, Cdk5 activity was decreased, PP1 activity was increased, and tau phosphorylation was reduced at both proline-directed and non-proline-directed sites. | Proline | microtubule associated protein tau | Homo sapiens |
| 7 | When Cdk5 was inhibited, tau phosphorylation at both proline- and non-proline directed sites and PP1 phosphorylation were blocked, indicating that Egr-1 acts through Cdk5. | Proline | microtubule associated protein tau | Homo sapiens |
| 8 | When Cdk5 was inhibited, tau phosphorylation at both proline- and non-proline directed sites and PP1 phosphorylation were blocked, indicating that Egr-1 acts through Cdk5. | Proline | microtubule associated protein tau | Homo sapiens |