Pub. Date : 2011 Aug
PMID : 21487789
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Further studies revealed that lycopene suppressed the production of tumor necrosis factor-alpha (TNF-alpha) and activation of nuclear factor-kappaB (NF-kappaB), CD14 and Toll-like receptor-4 (TLR4). | Lycopene | tumor necrosis factor | Homo sapiens |
| 2 | Further studies revealed that lycopene suppressed the production of tumor necrosis factor-alpha (TNF-alpha) and activation of nuclear factor-kappaB (NF-kappaB), CD14 and Toll-like receptor-4 (TLR4). | Lycopene | tumor necrosis factor | Homo sapiens |
| 3 | CONCLUSION: These findings suggest that lycopene has barrier integrity activity, and inhibitory activity on cell adhesion and migration to endothelial cells by blocking the activation of NF-kappaB, CD14 and TLR4 expression and production of TNF-alpha, thereby endorsing its usefulness as therapy for vascular inflammatory diseases. | Lycopene | tumor necrosis factor | Homo sapiens |