Title : Hypoxanthine guanine phosphoribosyltransferase distorts the purine ring of nucleotide substrates and perturbs the pKa of bound xanthosine monophosphate.

Pub. Date : 2011 May 17

PMID : 21486037






1 Functional Relationships(s)
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1 We used ultraviolet resonance Raman spectroscopy to study the complexes of HGPRT with products (IMP, GMP, and XMP), in both organisms, in resonance with the purine nucleobase electronic absorption. Inosine Monophosphate hypoxanthine phosphoribosyltransferase 1 Homo sapiens