Title : Lithocholic acid is an Eph-ephrin ligand interfering with Eph-kinase activation.

Pub. Date : 2011 Mar 30

PMID : 21479221






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Conversely, LCA inhibited EphA2 phosphorylation induced by ephrinA1-Fc in PC3 and HT29 human prostate and colon adenocarcinoma cell lines (IC(50) = 48 and 66 microM, respectively) without affecting cell viability or other receptor tyrosine-kinase (EGFR, VEGFR, IGFR1beta, IRKbeta) activity. Lithocholic Acid epidermal growth factor receptor Homo sapiens