Title : A novel agonist of PPAR-γ based on barbituric acid alleviates the development of non-alcoholic fatty liver disease by regulating adipocytokine expression and preventing insulin resistance.

Pub. Date : 2011 Jun 1

PMID : 21463618






3 Functional Relationships(s)
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1 A novel agonist of PPAR-gamma based on barbituric acid alleviates the development of non-alcoholic fatty liver disease by regulating adipocytokine expression and preventing insulin resistance. barbituric acid peroxisome proliferator activated receptor gamma Homo sapiens
2 Recently, a new series of PPARgamma ligands based on barbituric acid has been designed, in which 5-(4-(benzyloxy)benzylidene)pyrimidine-2,4,6(1H,3H,5H)-trione (SKLB102) showed a high affinity with PPARgamma. barbituric acid peroxisome proliferator activated receptor gamma Homo sapiens
3 Recently, a new series of PPARgamma ligands based on barbituric acid has been designed, in which 5-(4-(benzyloxy)benzylidene)pyrimidine-2,4,6(1H,3H,5H)-trione (SKLB102) showed a high affinity with PPARgamma. barbituric acid peroxisome proliferator activated receptor gamma Homo sapiens