Title : In vitro metabolism of glycyrrhetic acid by human cytochrome P450.

Pub. Date : 2011 Jan

PMID : 21462897






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The results indicated that GA was metabolized mainly by CYP3A4. Glycyrrhetinic Acid cytochrome P450 family 3 subfamily A member 4 Homo sapiens
2 At concentration up to 50 micromol x L(-1), GA inhibited CYP2C19, CYP2C9 and CYP3A4 enzyme activities with the inhibitory potencies up to 50%. Glycyrrhetinic Acid cytochrome P450 family 3 subfamily A member 4 Homo sapiens