Pub. Date : 2011 Apr
PMID : 21462331
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | This study also showed that tumor necrosis factor alpha (TNF-alpha) induced SPI-3 mRNA expression in HT-29 human colon cancer cells, and vitamin B6 (pyridoxal hydrochloride) pretreatment of HT-29 cells inhibited TNF -induced mRNA expression of SPI-3. | Vitamin B 6 | tumor necrosis factor | Homo sapiens |
| 2 | Vitamin B6 inhibited TNF-alpha-induced NF-kappaB activation via suppression of IkappaBalpha degradation in HT-29 cells. | Vitamin B 6 | tumor necrosis factor | Homo sapiens |
| 3 | HT-29 cells stably expressing epitope-tagged ubiquitin were generated and vitamin B6 pretreatment was shown to inhibit ubiquitination of the IkB protein in response to TNF-alpha-i. | Vitamin B 6 | tumor necrosis factor | Homo sapiens |