Title : Characterization of human breast cancer cell lines for the studies on p53 in chemical carcinogenesis.

Pub. Date : 2011 Aug

PMID : 21457773






6 Functional Relationships(s)
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1 The activation of benzo(a)pyrene (BP), a model compound of polycyclic aromatic hydrocarbons, to its genotoxic BP-diolepoxide (BPDE) and p53 response and cell viability after BP exposure, and the p53 status in these cell lines were analyzed. Benzo(a)pyrene tumor protein p53 Homo sapiens
2 The activation of benzo(a)pyrene (BP), a model compound of polycyclic aromatic hydrocarbons, to its genotoxic BP-diolepoxide (BPDE) and p53 response and cell viability after BP exposure, and the p53 status in these cell lines were analyzed. Benzo(a)pyrene tumor protein p53 Homo sapiens
3 The activation of benzo(a)pyrene (BP), a model compound of polycyclic aromatic hydrocarbons, to its genotoxic BP-diolepoxide (BPDE) and p53 response and cell viability after BP exposure, and the p53 status in these cell lines were analyzed. Benzo(a)pyrene tumor protein p53 Homo sapiens
4 The activation of benzo(a)pyrene (BP), a model compound of polycyclic aromatic hydrocarbons, to its genotoxic BP-diolepoxide (BPDE) and p53 response and cell viability after BP exposure, and the p53 status in these cell lines were analyzed. Benzo(a)pyrene tumor protein p53 Homo sapiens
5 After BP-treatment the strongest p53 protein induction and phosphorylation at serine 392 was found in ZR-75-1 cells with a wt TP53 gene. Benzo(a)pyrene tumor protein p53 Homo sapiens
6 After BP-treatment the strongest p53 protein induction and phosphorylation at serine 392 was found in ZR-75-1 cells with a wt TP53 gene. Benzo(a)pyrene tumor protein p53 Homo sapiens