Title : Wnt/β-catenin signaling pathway and thioredoxin-interacting protein (TXNIP) mediate the "glucose sensor" mechanism in metastatic breast cancer-derived cells MDA-MB-231.

Pub. Date : 2012 Feb

PMID : 21448924






1 Functional Relationships(s)
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1 The inhibition of both the hexosamine pathway and N-linked glycosylation along with Wnt signaling pathway by sFRP1 and DKK1 is associated with significant decrease of the protein levels of GSK3beta, beta-catenin, and TXNIP RNA. Hexosamines dickkopf WNT signaling pathway inhibitor 1 Homo sapiens