Pub. Date : 2011 Apr
PMID : 21448716
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We experimentally evaluated by mutational analysis the contribution of residues of rTRPV1 contributing to ligand binding by the prototypical TRPV1 agonists, capsaicin and resiniferatoxin (RTX). | resiniferatoxin | transient receptor potential cation channel, subfamily V, member 1 | Rattus norvegicus |
| 2 | We experimentally evaluated by mutational analysis the contribution of residues of rTRPV1 contributing to ligand binding by the prototypical TRPV1 agonists, capsaicin and resiniferatoxin (RTX). | resiniferatoxin | transient receptor potential cation channel, subfamily V, member 1 | Rattus norvegicus |
| 3 | We experimentally evaluated by mutational analysis the contribution of residues of rTRPV1 contributing to ligand binding by the prototypical TRPV1 agonists, capsaicin and resiniferatoxin (RTX). | resiniferatoxin | transient receptor potential cation channel, subfamily V, member 1 | Rattus norvegicus |
| 4 | We experimentally evaluated by mutational analysis the contribution of residues of rTRPV1 contributing to ligand binding by the prototypical TRPV1 agonists, capsaicin and resiniferatoxin (RTX). | resiniferatoxin | transient receptor potential cation channel, subfamily V, member 1 | Rattus norvegicus |
| 5 | Additionally, the binding mode of a simplified RTX (sRTX) ligand as predicted by the modeling agreed well with those of capsaicin and RTX, accounting for the high binding affinity of the sRTX ligand for TRPV1. | resiniferatoxin | transient receptor potential cation channel, subfamily V, member 1 | Rattus norvegicus |