Title : Cytochrome P450-dependent metabolism in HepaRG cells cultured in a dynamic three-dimensional bioreactor.

Pub. Date : 2011 Jul

PMID : 21436404






1 Functional Relationships(s)
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1 The activity of drug-metabolizing cytochrome P450 (P450) enzymes was investigated by a cocktail of substrates for CYP1A1/2 (phenacetin), CYP2C9 (diclofenac), CYP2B6 (bupropion), and CYP3A4 (midazolam). Phenacetin cytochrome P450 family 1 subfamily A member 1 Homo sapiens