Title : Intracellular inhibition of mono(ADP-ribosylation) by meta-iodobenzylguanidine: specificity, intracellular concentration and effects on glucocorticoid-mediated cell lysis.

Pub. Date : 1990 Aug 13

PMID : 2143421






2 Functional Relationships(s)
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1 Poly-ADPRP was inhibited by nicotinamide (IC50 = 0.03 mM) and by 3-aminobenzamide (IC50 less than or equal to 0.03 mM) but was insensitive to MIBG. Niacinamide poly (ADP-ribose) polymerase family, member 1 Mus musculus
2 In contrast, inhibition of poly-ADPRP by 3-aminobenzamide or nicotinamide (1 mM each) did not confer susceptibility to refractory cells but enhanced the lytic process in the sensitive subline L1210-H7 or in L1210-wt cells sensitized by MIBG. Niacinamide poly (ADP-ribose) polymerase family, member 1 Mus musculus