Title : Design, synthesis and biological characterization of novel inhibitors of CD38.

Pub. Date : 2011 May 7

PMID : 21431168






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The crystal structure of CD38/Compound 4 complex and computer simulation of Compound 7 docking to CD38 show a significant role of the nicotinamide moiety and the distal aromatic group of the compounds for substrate recognition by the active site of CD38. Niacinamide CD38 molecule Homo sapiens
2 The crystal structure of CD38/Compound 4 complex and computer simulation of Compound 7 docking to CD38 show a significant role of the nicotinamide moiety and the distal aromatic group of the compounds for substrate recognition by the active site of CD38. Niacinamide CD38 molecule Homo sapiens
3 The crystal structure of CD38/Compound 4 complex and computer simulation of Compound 7 docking to CD38 show a significant role of the nicotinamide moiety and the distal aromatic group of the compounds for substrate recognition by the active site of CD38. Niacinamide CD38 molecule Homo sapiens