Title : The activation of protein kinase C is not necessary for the monoclonal antibody-induced modulation of CD3 and CD4 antigens.

Pub. Date : 1990 May

PMID : 2141572






1 Functional Relationships(s)
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1 We studied the effect of staurosporine, a potent inhibitor of protein kinase C (PKC) activity, on the phorbol ester- or monoclonal antibody (mAb)-induced modulation of CD3 and CD4 surface antigens. Phorbol Esters CD4 molecule Homo sapiens