Pub. Date : 2011 Nov
PMID : 21404072
12 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Effect of UDP-glucuronosyltransferase 2B15 polymorphism on bisphenol A glucuronidation. | bisphenol A | UDP glucuronosyltransferase family 2 member B15 | Homo sapiens |
| 2 | Bisphenol A (BPA) is one of a number of potential endocrine-disrupting chemicals, which are metabolized mainly by UDP-glucuronosyltransferase 2B15 (UGT2B15) in humans. | bisphenol A | UDP glucuronosyltransferase family 2 member B15 | Homo sapiens |
| 3 | Bisphenol A (BPA) is one of a number of potential endocrine-disrupting chemicals, which are metabolized mainly by UDP-glucuronosyltransferase 2B15 (UGT2B15) in humans. | bisphenol A | UDP glucuronosyltransferase family 2 member B15 | Homo sapiens |
| 4 | Bisphenol A (BPA) is one of a number of potential endocrine-disrupting chemicals, which are metabolized mainly by UDP-glucuronosyltransferase 2B15 (UGT2B15) in humans. | bisphenol A | UDP glucuronosyltransferase family 2 member B15 | Homo sapiens |
| 5 | Bisphenol A (BPA) is one of a number of potential endocrine-disrupting chemicals, which are metabolized mainly by UDP-glucuronosyltransferase 2B15 (UGT2B15) in humans. | bisphenol A | UDP glucuronosyltransferase family 2 member B15 | Homo sapiens |
| 6 | However, the K (m), V (max), and CL (int) values of UGT2B15.3, UGT2B15.4, UGT2B15.6, and UGT2B15.7 having L86S, T352I, and/or K523T substitution(s) for BPA glucuronidation were comparable to those of UGT2B15.1. | bisphenol A | UDP glucuronosyltransferase family 2 member B15 | Homo sapiens |
| 7 | However, the K (m), V (max), and CL (int) values of UGT2B15.3, UGT2B15.4, UGT2B15.6, and UGT2B15.7 having L86S, T352I, and/or K523T substitution(s) for BPA glucuronidation were comparable to those of UGT2B15.1. | bisphenol A | UDP glucuronosyltransferase family 2 member B15 | Homo sapiens |
| 8 | However, the K (m), V (max), and CL (int) values of UGT2B15.3, UGT2B15.4, UGT2B15.6, and UGT2B15.7 having L86S, T352I, and/or K523T substitution(s) for BPA glucuronidation were comparable to those of UGT2B15.1. | bisphenol A | UDP glucuronosyltransferase family 2 member B15 | Homo sapiens |
| 9 | However, the K (m), V (max), and CL (int) values of UGT2B15.3, UGT2B15.4, UGT2B15.6, and UGT2B15.7 having L86S, T352I, and/or K523T substitution(s) for BPA glucuronidation were comparable to those of UGT2B15.1. | bisphenol A | UDP glucuronosyltransferase family 2 member B15 | Homo sapiens |
| 10 | However, the K (m), V (max), and CL (int) values of UGT2B15.3, UGT2B15.4, UGT2B15.6, and UGT2B15.7 having L86S, T352I, and/or K523T substitution(s) for BPA glucuronidation were comparable to those of UGT2B15.1. | bisphenol A | UDP glucuronosyltransferase family 2 member B15 | Homo sapiens |
| 11 | These findings suggest that D85Y substitution in UGT2B15 decreases enzymatic function and that the polymorphic alleles of UGT2B15 are closely associated with variations in the metabolism and toxicity of BPA. | bisphenol A | UDP glucuronosyltransferase family 2 member B15 | Homo sapiens |
| 12 | These findings suggest that D85Y substitution in UGT2B15 decreases enzymatic function and that the polymorphic alleles of UGT2B15 are closely associated with variations in the metabolism and toxicity of BPA. | bisphenol A | UDP glucuronosyltransferase family 2 member B15 | Homo sapiens |