Title : Role of intracellular calcium concentration and protein kinase C activation in IFN-gamma stimulation of U937 cells.

Pub. Date : 1990 Jun 1

PMID : 2140394






2 Functional Relationships(s)
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Protein Name
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1 IFN-gamma caused a rapid and concentration-dependent increase in [Ca2+]i, which was partly inhibited by calcium-free medium, diltiazem, and TMB-8. 8-(N,N-diethylamino)octyl-3,4,5-trimethoxybenzoate interferon gamma Homo sapiens
2 Induction of HLA-DR, Fc gamma R, CR3, and Mo3e Ag expression by IFN-gamma was blocked by concentrations of TMB-8 that inhibited an increase in [Ca2+]i, but not by protein kinase C inhibition by H-7 or inhibition of calmodulin with W-7. 8-(N,N-diethylamino)octyl-3,4,5-trimethoxybenzoate interferon gamma Homo sapiens