Title : Lycopene enhances docetaxel's effect in castration-resistant prostate cancer associated with insulin-like growth factor I receptor levels.

Pub. Date : 2011 Feb

PMID : 21403837






6 Functional Relationships(s)
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1 Lycopene enhances docetaxel"s effect in castration-resistant prostate cancer associated with insulin-like growth factor I receptor levels. Lycopene insulin like growth factor 1 receptor Homo sapiens
2 The growth-inhibitory effect of lycopene on PCa cell lines was positively associated with insulin-like growth factor I receptor (IGF-IR) levels. Lycopene insulin like growth factor 1 receptor Homo sapiens
3 The growth-inhibitory effect of lycopene on PCa cell lines was positively associated with insulin-like growth factor I receptor (IGF-IR) levels. Lycopene insulin like growth factor 1 receptor Homo sapiens
4 In addition, lycopene treatment enhanced the growth-inhibitory effect of docetaxel more effectively on DU145 cells with IGF-IR high expression than on those PCa cell lines with IGF-IR low expression. Lycopene insulin like growth factor 1 receptor Homo sapiens
5 In addition, lycopene treatment enhanced the growth-inhibitory effect of docetaxel more effectively on DU145 cells with IGF-IR high expression than on those PCa cell lines with IGF-IR low expression. Lycopene insulin like growth factor 1 receptor Homo sapiens
6 Lycopene inhibited IGF-IR activation through inhibiting IGF-I stimulation and by increasing the expression and secretion of IGF-BP3. Lycopene insulin like growth factor 1 receptor Homo sapiens