Title : CYP3A4 mediates growth of estrogen receptor-positive breast cancer cells in part by inducing nuclear translocation of phospho-Stat3 through biosynthesis of (±)-14,15-epoxyeicosatrienoic acid (EET).

Pub. Date : 2011 May 20

PMID : 21402692






1 Functional Relationships(s)
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1 Furthermore, eicosanoid profiling revealed that MCF7 cells synthesize EETs in a CYP3A4-dependent manner. Eicosanoids cytochrome P450 family 3 subfamily A member 4 Homo sapiens