Pub. Date : 2011 May 15
PMID : 21402092
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Pre- and post-treatment effect of physostigmine on soman-inhibited human erythrocyte and muscle acetylcholinesterase in vitro. | Physostigmine | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 2 | The present study was performed to investigate a possible pre- and post-treatment effect of physostigmine on soman-inhibited human AChE given at different time intervals before or after perfusion with soman by using a well-established dynamically working in vitro model for real-time analysis of erythrocyte and muscle AChE. | Physostigmine | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 3 | The major findings were that prophylactic physostigmine prevented complete inhibition of AChE by soman and resulted in partial spontaneous recovery of the enzyme by de-carbamylation. | Physostigmine | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 4 | Physostigmine given as post-treatment resulted in a time-dependent reduction of the protection from soman inhibition and recovery of AChE. | Physostigmine | acetylcholinesterase (Cartwright blood group) | Homo sapiens |