Pub. Date : 2011 Dec
PMID : 21400615
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Western blot analysis revealed that 5"-NIO inhibited activities of Raf-1 (S338), MEK1/2, ERK1/2, JNK, and c-Jun induced by EGF or TPA, respectively, whereas it did not affect autophosphorylation of epidermal growth factor receptor (EGFR) induced by EGF or TPA. | Tetradecanoylphorbol Acetate | jun proto-oncogene | Mus musculus |
| 2 | In addition, 5"-NIO exerted strong inhibitory effects on the EGF- or TPA-induced c-fos or c-jun transcriptional activity, and thereby inhibited the associated activator protein-1 (AP-1) transactivation activity induced by EGF or TPA. | Tetradecanoylphorbol Acetate | jun proto-oncogene | Mus musculus |
| 3 | In addition, 5"-NIO exerted strong inhibitory effects on the EGF- or TPA-induced c-fos or c-jun transcriptional activity, and thereby inhibited the associated activator protein-1 (AP-1) transactivation activity induced by EGF or TPA. | Tetradecanoylphorbol Acetate | jun proto-oncogene | Mus musculus |
| 4 | In addition, 5"-NIO exerted strong inhibitory effects on the EGF- or TPA-induced c-fos or c-jun transcriptional activity, and thereby inhibited the associated activator protein-1 (AP-1) transactivation activity induced by EGF or TPA. | Tetradecanoylphorbol Acetate | jun proto-oncogene | Mus musculus |
| 5 | In addition, 5"-NIO exerted strong inhibitory effects on the EGF- or TPA-induced c-fos or c-jun transcriptional activity, and thereby inhibited the associated activator protein-1 (AP-1) transactivation activity induced by EGF or TPA. | Tetradecanoylphorbol Acetate | jun proto-oncogene | Mus musculus |
| 6 | In addition, 5"-NIO exerted strong inhibitory effects on the EGF- or TPA-induced c-fos or c-jun transcriptional activity, and thereby inhibited the associated activator protein-1 (AP-1) transactivation activity induced by EGF or TPA. | Tetradecanoylphorbol Acetate | jun proto-oncogene | Mus musculus |