Title : Discovery of non-peptide, small molecule antagonists of α9α10 nicotinic acetylcholine receptors as novel analgesics for the treatment of neuropathic and tonic inflammatory pain.

Pub. Date : 2011 Apr 15

PMID : 21397497






1 Functional Relationships(s)
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1 A series of azaaromatic quaternary ammonium analogs has been discovered as potent and selective alpha9alpha10 nicotinic acetylcholine receptor (nAChR) antagonists. quaternary ammonium cholinergic receptor nicotinic alpha 4 subunit Homo sapiens