Title : CYP2A5 induction and hepatocellular stress: an adaptive response to perturbations of heme homeostasis.

Pub. Date : 2011 Feb

PMID : 21395539






1 Functional Relationships(s)
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1 Since CYP2A5 metabolizes various important xenobiotics including nicotine and pro-carcinogens such as nitrosamines and aflatoxin B(1), altered gene expression could affect tobacco addiction, hepatotoxicity and hepatocarcinogenesis. Nitrosamines cytochrome P450, family 2, subfamily a, polypeptide 5 Mus musculus