Title : Prolongation of cardiac ventricular repolarization under paliperidone: how and how much?

Pub. Date : 2011 Jun

PMID : 21394035






1 Functional Relationships(s)
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1 METHODS: (1) Patch-clamp experiments: Human ether-a-go-go-related gene (HERG)- or KCNQ1 + KCNE1-transfected cells were exposed to 0.1-100 mumol/L paliperidone (N = 39 cells, total) to assess the drug effect on HERG and KCNQ1 + KCNE1 currents. Paliperidone Palmitate potassium voltage-gated channel subfamily E regulatory subunit 1 Homo sapiens