Title : Lipid raft-dependent activation of dual oxidase 1/H2O2/NF-κB pathway in bronchial epithelial cells.

Pub. Date : 2011 Jul

PMID : 21389273






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Functionally, TNF-alpha-stimulated H(2)O(2) production was also blocked by MCD and DES (194.6 +- 15.4% vs. 90.6 +- 15.9% and 148.8 +- 20.4%), and the activation of the pivotal proinflammatory transcription factor, NF-kappaB, by TNF-alpha was reversed by MCD and DES as well as by small interfering RNAs of Duox1 or ASMase. Desipramine tumor necrosis factor Homo sapiens
2 Functionally, TNF-alpha-stimulated H(2)O(2) production was also blocked by MCD and DES (194.6 +- 15.4% vs. 90.6 +- 15.9% and 148.8 +- 20.4%), and the activation of the pivotal proinflammatory transcription factor, NF-kappaB, by TNF-alpha was reversed by MCD and DES as well as by small interfering RNAs of Duox1 or ASMase. Desipramine tumor necrosis factor Homo sapiens