Pub. Date : 2011 May 30
PMID : 21376710
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Aldose reductase (AKR1B1), which catalyzes the reduction of glucose to sorbitol and lipid aldehydes to lipid alcohols, has been shown to be involved in secondary diabetic complications including cataractogenesis. | Sorbitol | aldo-keto reductase family 1 member B1 | Rattus norvegicus |
| 2 | Aldose reductase (AKR1B1), which catalyzes the reduction of glucose to sorbitol and lipid aldehydes to lipid alcohols, has been shown to be involved in secondary diabetic complications including cataractogenesis. | Sorbitol | aldo-keto reductase family 1 member B1 | Rattus norvegicus |
| 3 | Biochemical analysis of lens homogenates showed that the AKR1B1 activity and sorbitol levels were significantly lower in sugar-treated AKR1B1 knockdown rat lenses as compared to WT rat lenses treated with 50mM glucose. | Sorbitol | aldo-keto reductase family 1 member B1 | Rattus norvegicus |