Title : An anticancer agent icaritin induces sustained activation of the extracellular signal-regulated kinase (ERK) pathway and inhibits growth of breast cancer cells.

Pub. Date : 2011 May 11

PMID : 21376032






1 Functional Relationships(s)
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1 At concentrations of 2-3 muM, icaritin induced cell cycle arrest at the G(2)/M phase accompanied by a down-regulation of the expression levels of the G(2)/M regulatory proteins such as cyclinB, cdc2 and cdc25C. icaritin cyclin dependent kinase 1 Homo sapiens