Title : An anticancer agent icaritin induces sustained activation of the extracellular signal-regulated kinase (ERK) pathway and inhibits growth of breast cancer cells.

Pub. Date : 2011 May 11

PMID : 21376032






2 Functional Relationships(s)
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1 Icaritin at concentrations of 4-5 muM, however, induced apoptotic cell death characterized by the accumulation of the annexin V- and propidium iodide-positive cells, cleavage of poly ADP-ribose polymerase (PARP) and down-regulation of the Bcl-2 expression. icaritin poly(ADP-ribose) polymerase 1 Homo sapiens
2 Icaritin at concentrations of 4-5 muM, however, induced apoptotic cell death characterized by the accumulation of the annexin V- and propidium iodide-positive cells, cleavage of poly ADP-ribose polymerase (PARP) and down-regulation of the Bcl-2 expression. icaritin poly(ADP-ribose) polymerase 1 Homo sapiens