Title : Inhibitory effects of herbal alkaloids on the tumor necrosis factor-α and nitric oxide production in lipopolysaccharide-stimulated RAW264 macrophages.

Pub. Date : 2011

PMID : 21372424






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1 Inhibitory effects of herbal alkaloids on the tumor necrosis factor-alpha and nitric oxide production in lipopolysaccharide-stimulated RAW264 macrophages. Alkaloids tumor necrosis factor Mus musculus
2 Since less attention has been paid to alkaloids in the diets than to polyphenols in this regard, we aimed at investigating anti-inflammatory activity of herb-derived alkaloids through suppression of TNF-alpha and NO production in lipopolysaccharide (LPS)-stimulated mouse RAW264 and/or human THP-1 cells. Alkaloids tumor necrosis factor Mus musculus
3 In conclusion, some herbal alkaloids like harmine, in spite of lacking antioxidative property, have potential as anti-inflammatory agents that strongly suppress TNF-alpha and NO production by a unique mechanism. Alkaloids tumor necrosis factor Mus musculus