Title : Effect of quercetin and glucuronide metabolites on the monoamine oxidase-A reaction in mouse brain mitochondria.

Pub. Date : 2011 Jul-Aug

PMID : 21371861






4 Functional Relationships(s)
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1 The effect of quercetin and its antioxidative metabolite quercetin 3-glucuronide (Q3GA) on the activity of mouse brain mitochondrial monoamine oxidase-A (MAO-A) was evaluated by measuring the deamination product of serotonin, 5-hydroxyindole acetaldehyde (5-HIAL). Serotonin monoamine oxidase A Mus musculus
2 The effect of quercetin and its antioxidative metabolite quercetin 3-glucuronide (Q3GA) on the activity of mouse brain mitochondrial monoamine oxidase-A (MAO-A) was evaluated by measuring the deamination product of serotonin, 5-hydroxyindole acetaldehyde (5-HIAL). Serotonin monoamine oxidase A Mus musculus
3 METHODS: An ultraviolet high-performance liquid chromatographic analysis was applied to measure the 5-HIAL generated by the reaction of MAO-A with serotonin. Serotonin monoamine oxidase A Mus musculus
4 Q3GA inhibited the generation of hydrogen peroxide from the MAO-A reaction with serotonin. Serotonin monoamine oxidase A Mus musculus