Title : S1P lyase regulates DNA damage responses through a novel sphingolipid feedback mechanism.

Pub. Date : 2011 Feb 10

PMID : 21368890






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 SPL acts through a novel feedback mechanism that amplifies stress-induced ceramide accumulation, and downregulation/inhibition of either SPL or ASMase prevents premature cell cycle progression and mitotic death. Ceramides sphingosine-1-phosphate lyase 1 Homo sapiens