Title : Mathematical modeling predicts synergistic antitumor effects of combining a macrophage-based, hypoxia-targeted gene therapy with chemotherapy.

Pub. Date : 2011 Apr 15

PMID : 21363914






2 Functional Relationships(s)
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1 Here, we use a new mathematical model to compare the effects of conventional cyclophosphamide therapy with those induced when macrophages are used to deliver hypoxia-inducible cytochrome P450 to locally activate cyclophosphamide. Cyclophosphamide cytochrome P450 family 4 subfamily F member 3 Homo sapiens
2 Here, we use a new mathematical model to compare the effects of conventional cyclophosphamide therapy with those induced when macrophages are used to deliver hypoxia-inducible cytochrome P450 to locally activate cyclophosphamide. Cyclophosphamide cytochrome P450 family 4 subfamily F member 3 Homo sapiens