Title : GABA(B) receptor antibodies in limbic encephalitis and anti-GAD-associated neurologic disorders.

Pub. Date : 2011 Mar 1

PMID : 21357831






6 Functional Relationships(s)
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Protein Name
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1 GABA(B) receptor antibodies in limbic encephalitis and anti-GAD-associated neurologic disorders. gamma-Aminobutyric Acid glutamate decarboxylase 1 Homo sapiens
2 BACKGROUND: gamma-Aminobutyric acid-B receptor antibodies (GABA(B)R-ab) were recently described in 15 patients with limbic encephalitis (LE), associated with small-cell lung cancer (SCLC) or with concurrent glutamic acid decarboxylase (GAD) antibodies. gamma-Aminobutyric Acid glutamate decarboxylase 1 Homo sapiens
3 BACKGROUND: gamma-Aminobutyric acid-B receptor antibodies (GABA(B)R-ab) were recently described in 15 patients with limbic encephalitis (LE), associated with small-cell lung cancer (SCLC) or with concurrent glutamic acid decarboxylase (GAD) antibodies. gamma-Aminobutyric Acid glutamate decarboxylase 1 Homo sapiens
4 We analyzed the frequency of GABA(B)R-ab in 147 patients with LE or neurologic syndromes associated with GAD-ab. gamma-Aminobutyric Acid glutamate decarboxylase 1 Homo sapiens
5 However, one patient with GAD-ab, paraneoplastic cerebellar ataxia, and anaplastic carcinoid of the thymus also presented GABA(B)R-ab. gamma-Aminobutyric Acid glutamate decarboxylase 1 Homo sapiens
6 In patients with GAD-ab, the frequency of GABA(B)R-ab is low and only observed in the context of cancer. gamma-Aminobutyric Acid glutamate decarboxylase 1 Homo sapiens