Title : β-Caryophyllene inhibits dextran sulfate sodium-induced colitis in mice through CB2 receptor activation and PPARγ pathway.

Pub. Date : 2011 Mar

PMID : 21356367






3 Functional Relationships(s)
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1 beta-Caryophyllene inhibits dextran sulfate sodium-induced colitis in mice through CB2 receptor activation and PPARgamma pathway. caryophyllene peroxisome proliferator activated receptor gamma Mus musculus
2 The use of the CB2 antagonist AM630 or the PPARgamma antagonist GW9662 significantly reversed the protective effect of BCP. caryophyllene peroxisome proliferator activated receptor gamma Mus musculus
3 These results demonstrate that the anti-inflammatory effect of BCP involves CB2 and the PPARgamma pathway and suggest BCP as a possible therapy for the treatment of inflammatory bowel disease. caryophyllene peroxisome proliferator activated receptor gamma Mus musculus