Title : Variability in response to clopidogrel: how important are pharmacogenetics and drug interactions?

Pub. Date : 2011 Oct

PMID : 21352268






1 Functional Relationships(s)
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1 In particular, omeprazole has been shown to inhibit the CYP-mediated metabolism of clopidogrel, and some studies have shown that the combination was associated with a higher incidence of cardiovascular adverse reactions than clopidogrel given alone. Omeprazole cytochrome P450 family 4 subfamily F member 3 Homo sapiens