Pub. Date : 2011 Oct
PMID : 21352268
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The main enzyme responsible for activating clopidogrel is the cytochrome P450 (CYP) isoenzyme CYP2C19, which is polymorphic. | Clopidogrel | cytochrome P450 family 4 subfamily F member 3 | Homo sapiens |
| 2 | The main enzyme responsible for activating clopidogrel is the cytochrome P450 (CYP) isoenzyme CYP2C19, which is polymorphic. | Clopidogrel | cytochrome P450 family 4 subfamily F member 3 | Homo sapiens |
| 3 | In particular, omeprazole has been shown to inhibit the CYP-mediated metabolism of clopidogrel, and some studies have shown that the combination was associated with a higher incidence of cardiovascular adverse reactions than clopidogrel given alone. | Clopidogrel | cytochrome P450 family 4 subfamily F member 3 | Homo sapiens |