Pub. Date : 2010 Dec 15
PMID : 21351272
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Here we evaluate interactions between 4 statins (lovastatin, atorvastatin, fluvastatin and rosuvastatin) and P-gp, at both the molecular level using purified P-gp and at the cellular level using human MDR tumor cells. | Rosuvastatin Calcium | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 2 | Finally, fluvastatin and rosuvastatin only interacted with P-gp in vitro at high concentrations and did not inhibit doxorubicin transport in MDR cells. | Rosuvastatin Calcium | ATP binding cassette subfamily B member 1 | Homo sapiens |