Title : TRPV1 antagonist can suppress the atopic dermatitis-like symptoms by accelerating skin barrier recovery.

Pub. Date : 2011 Apr

PMID : 21345654






3 Functional Relationships(s)
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Protein Name
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1 BACKGROUND: Transient receptor potential vanilloid type 1 (TRPV1) is a cation channel activated by diverse obnoxious stimuli like capsaicin, low pH or heat. Capsaicin transient receptor potential cation channel, subfamily V, member 1 Mus musculus
2 BACKGROUND: Transient receptor potential vanilloid type 1 (TRPV1) is a cation channel activated by diverse obnoxious stimuli like capsaicin, low pH or heat. Capsaicin transient receptor potential cation channel, subfamily V, member 1 Mus musculus
3 This potent TRPV1 antagonistic activity in keratinocytes was manifested in vivo as the blockade of capsaicin-induced blood perfusion increase, and the accelerated barrier recovery from tape-stripping-induced barrier damages in hairless mice. Capsaicin transient receptor potential cation channel, subfamily V, member 1 Mus musculus