Title : Natural osmolytes remodel the aggregation pathway of mutant huntingtin exon 1.

Pub. Date : 2011 Mar 29

PMID : 21332223






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Trimethylamine N-oxide (TMAO) and proline redirect amyloid fibrillogenesis of the pathological huntingtin exon 1 to nonamyloidogenic amorphous assemblies via two dissimilar molecular mechanisms. Proline huntingtin Homo sapiens